Mouth lesions
Adult: Apply 8.7% gel on affected area.
Oral
Fever, Pain
Adult: 435-870 mg every 4 hr when required.
Oral
Rheumatic disorders
Adult: 4.8-7.2 g daily in divided doses.
Chỉ định và Liều dùng
Buccal
Mouth lesions Adult: Apply 8.7% gel on affected area. Oral Fever, Pain Adult: 435-870 mg every 4 hr when required. Oral Rheumatic disorders Adult: 4.8-7.2 g daily in divided doses.
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Chống chỉ định
Haemophilia, haemorrhagic disorders, gout, history of hypersensitivity to salicylates. Severe renal or hepatic impairment; childn <12 yrs. Pregnancy and lactation.
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Thận trọng
Peptic ulcers, errosive gastritis; asthma, allergic disorders; renal and hepatic impairment; dehydrated patients; uncontrolled hypertension; elderly.
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Tác dụng không mong muốn
GI disorders, fatigue, hypersensitivity reactions, skin eruptions, haemolytic anaemia, weakness, dyspnoea; local irritation (rectally); Reye's syndrome.
Potentially Fatal: Paroxysmal bronchospasm; hepatotoxicity; renal impairment; thrombocytopenia, iron-deficiency anaemia, occult bleeding, leukopenia; mild chronic salicylate intoxication. |
Tương tác
Increased toxicity of warfarin. Antacids may reduce salicylate effects. Increased risk of GI bleeding when used with corticosteroids.
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Ảnh hưởng đến kết quả xét nghiệm
Interfere with thyroid function test.
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Tác dụng
Description:
Mechanism of Action: Choline salicylate alleviates pain by inhibition of prostaglandin synthesis and reduce fever by acting on the hypothalamus heat-regulating center. It also blocks the generation of impulses. Onset: 1-2 hr. |
Phân loại MIMS
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